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・ Cachrys
・ Cacht
・ Cacht ingen Ragnaill
・ Cachua
・ Cachucha
・ Cachucha peppers
・ Cachuela Esperanza
・ Cachupa
・ Cachupoy
・ Cache Creek Group
・ Cache Creek landfill
・ Cache Creek Terrane
・ Cache Creek Wilderness
・ Cache Creek, British Columbia
・ Cache Discovery Protocol
Cache domain
・ Cache Formation
・ Cache Heights
・ Cache High School
・ Cache Hill
・ Cache invalidation
・ Cache IQ
・ Cache La Poudre River
・ Cache La Poudre River Corridor National Heritage Area
・ Cache La Poudre Wilderness
・ Cache language model
・ Cache manifest in HTML5
・ Cache Meta Language
・ Cache National Forest
・ Cache on a stick


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Cache domain : ウィキペディア英語版
Cache domain

In molecular biology, the cache domain is an extracellular protein domain that is predicted to have a role in small-molecule recognition in a wide range of proteins, including the animal dihydropyridine-sensitive voltage-gated Ca2+ channel alpha-2delta subunit, and various bacterial chemotaxis receptors. The name Cache comes from CAlcium channels and CHEmotaxis receptors. This domain consists of an N-terminal part with three predicted strands and an alpha-helix, and a C-terminal part with a strand dyad followed by a relatively unstructured region. The N-terminal portion of the (unpermuted) Cache domain contains three predicted strands that could form a sheet analogous to that present in the core of the PAS domain structure. Cache domains are particularly widespread in bacteria such as ''Vibrio cholerae''. The animal calcium channel alpha-2delta subunits might have acquired a part of their extracellular domains from a bacterial source. The Cache domain appears to have arisen from the GAF-PAS fold despite their divergent functions.
==References==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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